Stephen Partridge was born on 16 Apr 1706 in Medfield, Massachusetts to John Partridge and Elizabeth Adams. He died on 10 Mar 1741/42 in Medway, Massachusetts. He married Mary MacCane (daughter of Daniel MacCane and Mary Heaton) on 07 Apr 1737 in Boston, Massachusetts. She was born on 25 May 1710 in Wrentham, Massachusetts.
Stephen inherited his father's homestead in East Medway, Massachusetts.
Stephen Partridge and Mary MacCane had the following children:
- Mary Partridge (was born on 20 Jun 1738 in Medway, Massachusetts. She married Joseph Baxter (son of John Baxter and Rebecca Fisher) on 29 Jan 1760 in Medfield, Massachusetts. He was born on 05 Feb 1733/34 in Medfield.
- Azuba Partridge (was born on 16 Apr 1742 in Medfield. She married Aaron Gardner (son of Addington Gardner and Mary Bryant) on 25 Dec 1765 in Medway. He was born on 20 Mar 1740/41 in Sherborn, Massachusetts.